EBioMedicine

Novel findings from a preclinical head-to-head comparison show that administering a COVID-19 vaccine as a nasal spray rather than a subcutaneous injection enhances the body’s long-term immune memory, thereby increasing the vaccine’s overall effectiveness. This research could pave the way for a COVID-19 vaccination strategy that depends on fewer boosters to achieve the same level of protection against SARS-CoV-2 viruses.

A research collaboration based in Japan has found a new pathological mediator of amyotrophic lateral sclerosis (ALS), which could have further implications for understanding the molecular breakdown that gives rise to the neurodegenerative disease that affects nearly half a million people around the world.