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 (Professor Datin Paduka Dr.) Aini Ideris
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(Professor Datin Paduka Dr.) Aini Ideris

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Country:
Malaysia

Institution:
Languages:
English; Malay

Areas of expertise:
Veterinary Sciences-Avian

Biography:
Professor Aini was selected to join a boarding school, Sekolah Tun Fatimah, Johor Bahru, for her secondary education. She has been very active since then, being a Deputy Head Girl, Captain of School softball team and represented the school as well as Johor Bahru district in many games, athletic events and cultural activities.

At the tertiary level, Professor Dr. Aini Ideris graduated with Doctor of Veterinary Medicine (DVM) degree in 1979 from Universiti Pertanian Malaysia - UPM (currently, Universiti Putra Malaysia). She then joined UPM as a tutor and pursued her postgraduate study, at the University of Liverpool, England, receiving Masters in Veterinary Science (MVSc) degree in Avian Medicine, in 1981. While serving as a lecturer at UPM, she pursued her PhD degree on a part-time basis shuttling between UPM and University of Queensland, Australia, where she was co-supervised by Prof Peter Spradbrow, a world renowned virologist. She was awarded PhD in 1989 by UPM. She later went on to do her postdoctoral training at the University of California, Davis, USA from 1990-1992. In 1993, she was awarded the Asian Development Bank Fellowship, for further postdoctoral training at Cornell University, USA, where she was involved in molecular biology research together with two other postdoctoral fellows.

At UPM, Professor Aini is involved in giving lectures, conducting practical classes and providing clinical training to undergraduate Doctor of Veterinary Medicine (DVM) students and postgraduate students. She has supervised the final year projects of more than 30 DVM students, graduated more than 20 Master students, and more than 15 PhD students. Though Prof Aini is being entrusted with heavy administrative duties as Dean of School of Graduate Studies, she is still involved in teaching and attend to clinical cases in the University Veterinary Teaching Hospital. Currently, Prof Aini supervises 8 Masters and 7 PhD students. She is also the external examiner for Master’s and PhD theses at several universities, including University of Queensland, Australia, and has been invited by other universities, to conduct courses on postgraduate supervision.

Professor Aini has been actively involved in research related to the control of poultry diseases and development of poultry vaccines. She has been the programme leader for research in avian health and is the programme leader for National Top-Down Animal Biotechnology projects. Her research interests are in avian respiratory and immunosuppressive diseases, such as, Newcastle disease, fowl pox, avian influenza, chicken infectious anaemia, infectious bursal disease and infectious bronchitis, the economically important and feared diseases in the avian world. Her great breakthrough in research was when she successfully cloned a new heat resistant Newcastle disease virus, V4-UPM, which can be administered not only by the conventional methods but can also be incorporated in the feed. This novel method of administrating vaccine in the feed has created a lot of interest worldwide.

Her research has led to the commercialisation of two poultry vaccines, namely: Newcastle disease vaccine (funded by the Australian Centre for International Agricultural Research) and tissue culture adapted fowl pox vaccine (funded by the National Science Council Malaysia) in 1995 and 1996 respectively. These two vaccines were among the first research products that have been successfully commercialised and also the first example of transfer of technology from the university to the industry, in Malaysia. As a recognition of her achievements in the successful commercialisation of poultry vaccines, she was awarded a special research grant by the Prime Minister’s Department in 1996 to further improve the facilities of her research laboratory and to enhance the development of vaccine technology in Malaysia, through biotechnology. Recently in 2005, her research team made another breakthrough. They successfully commercialised another important poultry vaccine, i.e. infectious bursal disease vaccine. They also developed rapid diagnostic methods for avian influenza (bird flu), which is a zoonotic disease. This diagnostic kit has been essential in the detection and monitoring of avian influenza outbreaks in Malaysia, in 2004 and 2005. The kit has been filed for patent and is undergoing further field testing towards commercialisation.

The commercialisation of Newcastle disease and Fowl pox vaccines in 1995 and 1996 respectively, is instrumental in the establishment of the first and the only local vaccine company in Malaysia. This has made a history in Malaysia. The two vaccines are sold not only in Malaysia but also in several other countries such as China, Indonesia, Phillippines, Myanmar, Timor Timor, Indonesia, countries under FAO and UNDP projects such as Kenya, Mozambique and Nigeria. The sale has exceeded RM3 million up to 2007. The company is in the process of registering the vaccines for sale in Thailand, Vietnam, Bangladesh, Pakistan and Saudi Arabia.

Prof. Aini’s current research involves, studies on the development of conventional and genetically engineered vaccines, as well as rapid diagnostic methods. She received research grants from the Ministry of Science, Technology and Innovation, National Cancer Council and also from international agencies such as Australian Centre for International Agricultural Research, and the International Foundation of Science, either as the main researcher or co-researcher. With her expertise and experience in disease control and vaccine development, she plays a big role in mentoring and guiding other junior researchers and has established a strong research team in avian health at the National level. Together, they have won many research awards at the national and international levels. Prof Aini is also the recipient of Vice Chancellor’s Fellowship (Excellence in Research, 2007) and the Institute of Bioscience’s Excellent Research award, 2007.

Prof. Aini has over 400 publications to her credit and is well known internationally among the avian veterinarians. As a result, she is honoured with invitations to present papers as a Keynote or Plenary Speaker at several national and international conferences, the most prestigious being, the 10th World Veterinary Poultry Science Congress, Sydney, Australia, 1993, the 4th ASIA-Pacific Poultry Health Conference, Melbourne, 1998, and the 21st World’s Poultry Congress, held in Montreal, Canada, in the year 2000. The others include, the Royal Thai Veterinary Congress, Bangkok, 2001, the 2nd International Virology Congress, Iran, 2004, International Biotechnology Congress BIOJeddah, Jeddah, Saudi Arabia, 2004, the Asia-Pacific Poultry Congress, Bangkok, March 2007, and Trends in Infectious Bursal Disease Vaccines, to be held in Bangladesh in November 2008. She has also been invited as a member of the Expert Panel in many meetings and strategic planning, concerning worldwide control of poultry diseases, together with experts from FAO, WHO, OIE and others.

Professor Aini has a wide experience in editorial work, serving not only the national journals, but also international journals. For the international journals, among others, she was an Associate Editor of the Asia Pacific Journal of Molecular Biology and Biotechnology, and the Editorial Advisory Board for Veterinary Microbiology Journal (based in Sweden). Currently she is a member of the Editorial Board for Korean Veterinary Journal and Advisory Board member for Avian Pathology journal (based in United Kingdom).

Professor Aini is also actively involved in many committees at the national and international levels as Chairman, or Executive Committee member. She is a panel member of several committees under the Ministry of Science, Technology and Innovation, Malaysia, in relation to evaluating biotechnology research projects and National Science Fellowship award. Currently, she is the National Coordinator of Animal Biotechnology research, responsible for planning Animal Biotechnology programmes in the country and coordinating researchers under Top-Down projects. She is also the Chairman for Animal Biotechnology Technical Panel, under the National Institute of Agrobiotechnology, responsible for project evaluation and monitoring. Prof Aini was the Chairman of the Drafting Committee responsible for drafting the National Biotechnology Policy from 2001 to 2003. She was also in the Task Force, responsible for planning and providing advisory services for the recently established National Biotechnology Institutes (Agrobiotechnology Institute and Nutraceutical and Pharmaceutical Biotechnology Institute) under the National Biotechnology project, Malaysia. She is a member of the Advisory Committee to Ministry of Higher Education (MOHE) on Biotechnology and the Chairman for Graduate Employability Project under the National Higher Education Strategic Plan. At the international level, she was an alternate coordinator for ASEAN Network for Biotechnology in Animal Production and Health, FAO, and presently the ASIAN Representative/Correspondent for the International Network of Family Poultry Development, under the umbrella of FAO.

Prof. Aini has been very active in professional associations, either nationally or internationally. She was the Deputy Chairman for Veterinary Association Malaysia Education Trust Fund, the Honorary Treasurer for World’s Poultry Science Association – Malaysian Chapter, and member of World Veterinary Poultry Association. As an alumni of UPM, she was the EXCO member of UPM Alumni and EXCO of UPM Veterinary Alumni in the 1990s. She continues to support and be actively involved in the alumni activities. Besides professional associations, she is also involved in voluntary services. Among others, she was one of the Founder Committee members of the University Ladies Association (PERMATA) and active member of PUSPANITA Negeri Sembilan. Currently she is the EXCO member for National Cancer Council (MAKNA), member of Board of Directors, MAKNA Research Centre and also a member of the Investigating Tribunal Panel for the Advocates and Solicitors Disciplinary Board of the Bar Council, Malaysia, since 2004.

Prof Aini has a wide experience in organizing successfully a number of national and international workshops and conferences. She has also been a resource person in many workshops. In consultancy, she gives advices and provides avian health services to poultry farmers all over Malaysia.

In administration, Professor Aini has a long administrative experience. She was the Acting Head, Department of Veterinary Clinical Studies, in 1989 and 1990, Chairman of Veterinary Teaching Hospital from 1992 to 1998, Deputy Dean of Faculty of Veterinary Medicine, for 9 years, from 1992 to 2001, responsible for curriculum development and curriculum review, securing places for students’ practical training in Malaysia and abroad, and managing University Veterinary Hospital. She was also the pioneer team member in bringing Faculty of Veterinary Medicine to be the first Faculty successfully awarded ISO 9000 certification. Currently, she is the Dean, School of Graduate Studies, Universiti Putra Malaysia, a position she holds since May 2001. She is also the Chairman, of Malaysian Postgraduate Deans Council for IPTAs, since 2005. Under her leadership, the Council has contributed significantly to wards the development of postgraduate education in the country. The Council becomes an important component in MOHE for matters related to postgraduate studies.

In recognition of her research achievements, teaching, professional services, community services and other involvements at the national and international levels, Professor Aini received Excellent Service Certificates from the University every year, since 1992, and twice received the Excellent Service Award, in 1995 and 2005. She was promoted to an Associate Professor in 1991 and a Professor in Avian Medicine, in 1996 (Professor Aini was the first graduate of Universiti Pertanian Malaysia to be appointed as Professor in UPM). She was again promoted to a Senior Professor (Special Grade B) in 2001.

At the First Ladies’ Dialogue in conjunction with OIC meeting in 2003, she was selected as one of the 11 successful professional ladies in Malaysia to be introduced by the Malaysian First Lady, the Prime Minister’s wife.

Publications:
1. Bradbury, J. M. and I. Aini (1982). Abnormalities of turkey poults following infection with Mycoplasma iowae. Veterinary Record. 110: 559 560


2. Ibrahim, A.L., M.C. Lai and I. Aini (1983). Spray vaccination with an improved F Newcastle disease vaccine. A comparison of efficacy with the BI and La Sota vaccines. British Vet. Journal. 139: 213 219.


3. Aini, I. and A.L. Ibrahim (1986). Isolation of influenza A viruses from domestic ducks in Malaysia. Veterinary Record. 118:130.


4. Bradbury, J. M., I. Aini and Tin Tun Oo (1988). Mycoplasma Iowae infections in young turkeys. Avian Pathology. 17: 149 171.

5. Aini, I., A.L. Ibrahim and P.B. Spradbrow (1990). Vaccination of chickens against Newcastle disease with a food pellet vaccine. Avian Pathology. 19(2): 371 384.

6. Aini, I. (1990). Indigenous chicken production in South East Asia. World's Poultry Science Journal. 46(2) : 51 57.

7. Aini, I. (1990). Control of poultry diseases in Asia by vaccination. World's Poultry Science Journal. 46:125 132.

8. Aini, I., A.L. Ibrahim and P.B. Spradbrow (1990). Field trials of a food based vaccine to protect chickens against Newcastle disease. Research in Veterinary Science. 49:216 219.

9. Harith, M.I., I.P.R. Awang, D.J. Alexander, R.J. Manvell, I. Aini and A.L. Ibrahim (1990). Isolations of influenza A viruses from passerine birds in Malaysia. Vet. Record. 127: 528.


10. Bell, I.G., P.J. Nichollas, C. Norman, I. Aini and G.M. Cross (1991). The resistance of meat chickens vaccinated by aerosol with a live V4 Newcastle disease virus vaccine in the field to challenge with a velogenic Newcastle disease virus. Australian Veterinary Journal. 68(3): 97 101.

11. Jarra Jagne, I. Aini K.A. Schat, A. Fennell, and O. Touray (1991). Vaccination of village chickens in The Gambia against Newcastle disease using the heat resistant, food pelleted V4 vaccine. Avian Pathology. 20: 721 724.


12. Aini, I., A.L. Ibrahim and P.B. Spradbrow (1992). Efficacy of food pellet Newcastle disease vaccine: simulated village experiments. Jurnal Veterinar Malaysia. 4(2): 81 86.

13. Aini, I., L.M. Shih, A.E. Castro and Y.C. Zee (1993). Comparison of herpesvirus isolates from falcons, pigeons and psittacines by restriction endonuclease analysis. Journal of Wildlife Diseases. 20(2): 196 202.



14. Lee, C.C. I. Aini, B. Kawitha and S.M. Amin Babjee (1998). Parasites of birds (Columbiformes) in Peninsular Malaysia. Tropical Biomedicine. 15(2) : 29 36.


15. Fauziah, O., I. Aini, U. Chulan and A.L. Ibrahim. (1999). Pathogenicity of Velogenic Viscerotropic Newcastle disease virus in the bursa of Fabricius of vaccinated chickens. Jurnal Veterinar Malaysia 11(1): 13-18.

16. Hoque, M.M, A.R. Omar, L.K. Chong, M. Hair-Bejo, and I. Aini, (2001). Pathogenicity of Sspl positive infectious bursal disease virus and molecular charcterization of VP2 hypervariable region. Avian Pathology 30: 379-390.

17. Chong, L.K., A.R. Omar, K. Yusoff, M. Hair-Bejo and I. Aini, (2001). Nucleotide Sequence and phylogenetic analysis of the A segment of a very virulent infectious bursal disease virus. Acta Virologica 45: 217-226.

18. Hoque, M.M, Omar, A.R., Hair-Bejo, M. and Aini, I. (2002). Sequence and phylogenetic analysis of the VP2 gene of very infectious bursal disease virus isolates. Journal of Biochemistry, Molecular Biology and Biophysics. 6: 93-99.

19. Chowdhury, S.M.Z.H., Omar A.R., Aini, I., Hair-Bejo, M., Jamaluddin, A.A., Wan, K.L. and Kono, Y. (2002). Development of a modified method for sequencing high G:C regions in chicken anemia virus genome. Journal of Biochemistry, Molecular Biology and Biophysics. 6: 229-232.

20. Kianizadeh, M., Aini I., Omar, A.R., Yusoff, K., Sahrabadi, M., Kargar. (2002). Sequence and phylogenetic analysis of the fusion protein cleavage site of Newcastle disease virus field isolates from Iran. Acta Virologica 46: 247-251..


21. Narayani M., Fauziah, O, Abdul Rahman Omar and Aini I (2002). Cytotoxicity Assay and Transmission Electron Microscopy of MCF-7 Cancer Cell Line Treated with Local Strains of Newcastle. Annals of Microscopy 3.

22. Phong, S.F., Hair-Bejo, M., Omar, A.R. and Aini, I. (2002). Molecular characterization of Malaysian isolate of very virulent IBDV. Asia-Pacific Journal of Molecular Biology and Biotechnology. 10(2): 89-96.

23. Phong, S.F., Hair-Bejo, M., Omar, A.R. and I. Aini (2003). Sequence analysis of Malaysian infection bursal disease virus isolate and the use of reverse transcriptase nested polymerase chain reaction enzyme-linked immunosorbant assay for detection of VP2 hypervariable region. Avian Diseases, 47:149-154.


24. Chowdhury, S.M.Z.H, Omar, A.R., Aini, I., Hair-Bejo, M., Jamaluddin, A.A. Md-Zain, B.M. and Kono, Y. (2003). Pathogenicity, sequence and phylogenetic analysis of Malaysian chicken anaemia virus obtained after low and high passages in MSB-1 cells. Archives of Virology, 148: 2437-2448. .

25. Narayani, M., Fauziah, O., Omar, A. R and Aini, I. (2003). Cytotoxicity assay and transmission electron microscopy of MCF-7 cancer cell line treated with local strains of Newcastle disease virus. Annals of Microscopy 3:. 36-42.


26. Omar A.R., Aini I., Abdul Manaf A., Fauziah O., Yussof K., Jafri M.A., Haryati S.M.W., Madihah Z., and Narayani M. (2003) An Overview on the Development of Newcastle Disease Virus as an Anti-cancer Therapy. The Journal of Medical Sciences 10(1): 4 – 12.

27. Tan, S.W., Omar, A.R., Aini, I., Yusoff, K., Tan, T.S. (2004). Detection of Newcastle disease virus (NDV) using Sybr Green I real-time polymerase chain reaction. Acta Virologica, 48: 23-28.

28. Kong, L.L., Omar, A.R., Hair-Bejo, M., Aini, I. and H.F. Seow (2004). Quantitative analysis of viral RNA and apoptotic cells in bursa following infection with infectious bursal disease virus. Comparative Immunology, Microbiology & Infectious Diseases, 27:433-443.

29. Tan, D.Y., Hair-Bejo, M., Omar, A.R. and Aini, I (2004). Pathogenicity and molecular analysis of an infectious bursal disease virus isolated from Malaysian village chickens. Avian Diseases, 48(2):410-416.


30. Hasmah, S. Omar, A. R., Wan, K. F., Hair-Bejo, M. and Aini, I (2004). Genetic diversity of chicken anemia virus following cell culture passaging in MSB-1 cells. Acta Virologica 48: 85-89.


31. Hosseini S.D., Omar, A.R. and Aini, I. (2004). Molecular characterization of an infectious bursal disease virus isolated in Iran. Acta Virologica 48:79-83.

32. Tan, S. W., Omar, A.R., Aini, I., Yusoff, K., and Tan, W.S. (2005). Sequence analysis of the fusion (F) and matrix (M) genes of recently isolated Newcastle disease virus from Malaysia. Jurnal Veterinar Malaysia. 17(2):1-11

33. Nurulfiza, Hair Bejo, Omar, A.R., and Aini I. (2006). Molecular characterization of recent infectious bursal disease virus isolates from Malaysia. Acta Virologica 50: 47 - 53.



34. Chaharaein, B., Omar, A.R., Aini, I., Yusoff, K., and Hassan, S.S. (2006). RT-PCR-ELISA for rapid detection of avian influenza virus subtype H9N2. Archives of Virology. 151:2447 – 2459.

35. Omar, A.R., Chong, L.K. Hair-Bejo, M., and Aini, I. (2006). Efficacy of VP2 protein expressed in E. coli for protection against highly virulent infectious bursal disease virus. Journal of Veterinary Science. 7(3): 241-247.


36. Hosseini, S.D., Omar, A.R., Aini, I., and Ali A.M. (2007). Diagnostic potential of E coli expressed infectious bursal disease virus protein VPX. Acta Hungaria Veterinaria 55: 405-415. (JIF 0.5)

37. Ong, W.T., Omar, A.R., Aini, I. and Hassan, S.S. (2007). Development of multiplex real-time PCR assay using SYBR Green 1 chemistry for simultaneous detection and subtyping of H9N2 influenza virus type A. Journal of Virological Methods 144: 57-64. (JIF 2.1)

Abdullah, J.M., Ahmad, F., Ahmad, K.A., Ghazali, M.M., Jaafar, H., Ideris, A., Ali, A. M., Omar, A.R., Yusoff, K., Lila, M.A. and Othman, F. (2007). Molecular genetic analysis of BAX and cyclin D1 genes in patients with malignant glioma. Neurological Research 29: 239-242. (JIF 1.6).

*a full list of publications will be provided to anyone who is interested.
 
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