Angeli Ambayya

Angeli Ambayya is a Scientific Officer (Ministry of Health, Malaysia). She is passionate about research in the field of hemato-oncology.

Angeli Ambayya is a Scientific Officer in the Ministry of Health Malaysia since 2007. Previously, she was a Scientist at the Gribbles Pathology Malaysia (2006). Angeli specialises in flow cytometry, genetics and genomics of haematology malignancies. She is trained in flow cytometry and stem cell transplantation at the Royal Melbourne Hospital, Australia (2010) and the University of York, United Kingdom. She obtained her genomics and precision oncology certification from Harvard Medical School (USA) and underwent bioinformatics training at Newcastle University (United Kingdom) in 2019.

Angeli led several MOH Malaysia research projects, including Haematological Reference Intervals in a Multiethnic population that included 2725 subjects nationwide. She was also the project leader and principal investigator for several genetics and genomic projects on acute leukaemia patients.

Angeli has been awarded prestigious local and international awards that include Berend Houwen Travel Award (2015 and 2016), Mentee for the International Society for Laboratory Hematology (ISLH) (2017-2018), Best Abstract Awards by the Malaysian Society of Haematology (2016,2018,2020 and 2023), Travel Awardee by the International Society for Laboratory Haematology (2020 and 2023) and Best Abstract Award by the ICBMT Korea (2020) and Travel Award by ICBMT 2023.

She has been serving as a scientific committee for the ISLH since 2019 and a committee member for the International Scientific Webinar Organised by the Malaysian Association of Science Officers (PPSM). She is also an active reviewer for local and international journals that include Springer Nature, Wiley, PlosOne, etc. She has been invited as a speaker in several local and international conferences since 2011.

Selected publications

Angeli Ambayya, Rozaimi Razali, Sarina Sulong, Ezzanie Suffya Zulkefli, Yap Yee Yee, Jameela Sathar, Rosline Hassan. Genomic alterations, gene expression profiles, functional enrichment and prognostication of acute myeloid leukaemia-normal karyotype based on targeted next-generation sequencing. Scientific Reports (Under Review, IF :4.996, Q1)
Ambayya, A., Moorman, A.V.; Sathar, J.; Eswaran, J.; Sulong, S.; Hassan, R. Genetic Profiles and Risk Stratification in Adult De Novo Acute Myeloid Leukaemia in Relation to Age, Gender, and Ethnicity: A Study from Malaysia. Int. J. Mol. Sci. 2022, 23, 258. https://doi.org/10.3390/ijms23010258 (Published on 27th December 2021) (IF:5.924, Q1)
Ambayya, A.; Sathar, J.; Hassan, R. Neoteric Algorithm Using Cell Population Data (VCS Parameters) as a Rapid Screening Tool for Haematological Disorders. Diagnostics 2021, 11, 1652. https://doi.org/10.3390/diagnostics11091652 (Published on 9th September 2021) (IF:3.706, Q2)
Ambayya, A.; Sahibon, S.; Yang, T.W.; Zhang, Q.-Y.; Hassan, R.; Sathar, J. A Novel Algorithm Using Cell Population Data (VCS Parameters) as a Screening Discriminant between Alpha and Beta Thalassemia Traits. Diagnostics 2021, 11, 2163. https://doi .org/10.3390/diagnostics11112163 (Published on November 18 2021) (IF:3.706, Q2)
Ambayya A., Sasmita AO, Yegappan S, Sathar J (2019) Utilising Extended Red Blood Cell Parameters to Distinguish Iron-Deficient Erythropoiesis - Related Disorders in Malaysian Female Population. Int J Blood Res Disord 6:035. doi.org/10.23937/2469-5696/1410035.
Ambayya A., Zainina S., Sabariah M.N., Chang K.M., Lim S.M., Yegappan S. Microarray-Based Genomic Analysis Identifies Germline and Somatic Copy Number Variants and Loss of Heterozygosity in Acute Myeloid Leukaemia. (Mal J of Med&Health Sci 14(SP3 – Dec 2018):11-24.
Ambayya A., Andrew Octavian Sasmita, Jameela Sathar, Kian Meng Chang, Zainina Seman, Sabariah Md Noor, Subramanian Yegappan. Application of Molecular Karyotyping in Acute Myeloid Leukemia: A Review. International Journal of Biomedical Science and Engineering. Vol. 6, No. 2, 2018, pp. 20-31. doi: 10.11648/j.ijbse.20180602.11.
Ambayya A., Su A.T., Osman N.H., Nik-Samsudin N.R., Khalid K., et al. (2014) Haematological Reference Intervals in a Multiethnic Population. PLoS ONE 9(3): e91968. doi:10.1371/journal.pone.0091968. (Q1, IF 3.752)
Ambayya A., Zainina S., Sabariah M.N. (2014). Antigen expression pattern of acute promyelocytic leukaemia cases in Malaysia. The Medical Journal of Malaysia 69(2):64-9.
Ambayya A., Zainina S., Sabariah M.N. (2013). Recent advances in diagnosis of acute myeloid leukaemia: A review. Asian journal of multidisciplinary studies 1:5.