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 Professor M.R. Jisnuson SVASTI
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Name:
Professor M.R. Jisnuson SVASTI

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Country:
Thailand

Institution:
Languages:
Thai; English

Areas of expertise:
Protein Structure and Function, Molecular Enzymology, Genetic Diseases, Cancer Proteomics

Biography:
EDUCATION:

1968 B.A. (Hons) Natural Sciences (Biochemistry), Cambridge University, United Kingdom.
1972 M.A., Natural Sciences, Cambridge University, United Kingdom
1972 Ph.D., MRC Laboratory of Molecular Biology, Cambridge University, United Kingdom

PROFESSIONAL EXPERIENCE:

1982-present Professor, Department of Biochemistry, Faculty of Science, Mahidol University, Rama VI Road, Bangkok 10400, Thailand.
2001-present Head, Center for Excellence in Protein Structure and Function, Faculty of Science, Mahidol University, Bangkok 10400, Thailand
1990-present Head, Laboratory of Biochemistry, Chulabhorn Research Institute, Don Muang, Bangkok 10210, Thailand
1972-present Staff Member, Department of Biochemistry, Faculty of Science, Mahidol University, Rama VI Road, Bangkok 10400, Thailand
1980-1984 Chairman, Department of Biochemistry, Faculty of Science, Mahidol University
1982-1991 Board of Directors, Chumbot-Pantip Foundation
1984-present Board of Directors, Prajadhipok-Rambhai Barni Foundation
1985-present Board of Directors, Memorial Foundation for H.M. King Rama VII-Queen Rambhai Barni
1985-1987 Editor-in-Chief, Journal of the Science Society of Thailand, and Member, Executive Committee, Science Society of Thailand
1986-1987 Chairman, Biochemical Section, Science Society of Thailand
1996-1997 Associate Dean, Faculty of Science, Mahidol University
1997-1999 Vice-President for International Relations, Mahidol University
1979-1981 Member, Coordinating Committee, Asian Network of Biological Science
1980-1986 Treasurer, Federation of Asian & Oceanian Biochemists
1988-present Advisory Board, Biochemical Section, Science Society of Thailand
1990-present Board of Trustees, Cambridge-Thai Foundation
1990-1992 President, Federation of Asian and Oceanian Biochemists (FAOB)
1991-1998 Committee Member, National Research Council of Thailand (Agriculture & Biology Section)
1994 Chairman, Organising Committee, Eleventh FAOBMB Symposium on Biopolymers and Bioproducts: structure, function and applications, Bangkok, 15-18 November 1994
1996-2002 Member, Committee on Symposia, International Union of Biochemistry and Molecular Biology (IUBMB)
1996-present Thai Delegate to IUBMB
1998-present Governing Council, Asia-Pacific International Molecular Biology Network (A-IMBN)
2001-present Editor-in-Chief, ScienceAsia, and Member, Executive Committee, Science Society of Thailand
2001-present Membership Committee for Biochemistry and Biophysics, Third World Academy of Science
2002-present Committee Member, National Research Council of Thailand (Chemical Sciences & Pharmacy Section)
2002-present Honorary Jury, UNESCO-L'Oreal Women in Science Program, Thailand
2003-present Editorial Board, Molecules and Cells, Korean Society of Molecular and Cellular Biology
2003-present Member, Health Committee, EAGLES (European Action on Global Life Sciences)
2003-2004, 2006 External Assessor of Chulalongkorn University for the Office of National Education Standards and Quality Assessment
2004-present Council Member, Asian and Oceanian Human Proteome Organization
2004-present Member, University Council, Huachiew Chalermphrakiet University
2005-present University Council, Mahidol University, Bangkok

AWARDS AND HONOURS:

1972 Travel Fellowship, First International Symposium on Immunology, Gausdal, Norway
1974 Travel Fellowship, Third International Conference on Isozymes, New Haven, U.S.A.
1976 IUB Travel Fellowship, 10 th International Congress of Biochemistry, Hamburg, Germany
1982 Mahidol University Prize for Excellence in Research: “Chromatin Structure and Nucleic Basic Proteins in Mammalian Male Germ Cells” (with Nongnuj Tanphaichitr and Prasert Sobhon)
1994 Honorary Member, Federation of Asian and Oceanian Biochemists and Molecular Biologists, Inc. (FAOBMB)
1995 Honorary Member, Philippine Society of Biochemistry and Molecular Biology
1996 Elected Fellow, Third World Academy of Science (TWAS)
1997 Founding Member, Thailand Academy of Science and Technology (TAST)
1998 Member, Asia-Pacific International Molecular Biology Network
1998 Outstanding Researcher Award, Ministry of University Affairs
2001 Senior Research Scholar, Thailand Research Fund
2002 Outstanding Scientist of Thailand Award , Foundation for the Promotion of Science and Technology under the Patronage of His Majesty the King
2003 Outstanding Researcher, Chemical Sciences and Pharmacy Section, National Research Council of Thailand
2003 Outstanding Lecturer, Faculty Club, Faculty of Science, Mahidol University
2004 Exemplary Lecturer, Faculty Club, Mahidol University
2005 Outstanding Lecturer Award from the Council of the University Faculty Senates of Thailand

RESEARCH INTERESTS:

General interests in Protein Structure and Molecular Enzymology, especially:
Glycosidase enzymes and glycosides
Abnormal hemoglobins and inborn errors of metabolism
Proteomics of human cancer
Natural products with anti-cancer activity


Publications:
A. Research and Original Articles at International Level

1. Svasti, J. and Viriyachai, S. (1975) The properties of purified LDH-C4 from human testes. In Isozymes, Vol. 2. (Physiological Function). C.L. Market, ed., Academic Press, N.Y. pp 113-127.

2. Svasti, J. and Viriyachai, S. (1975) The purification of lactate dehydrogenase isozymes LDH-A4, LDH-B4, and LDH-C4 from human tissues. J. Sci. Soc. Thailand 1, 57-71.

3. Pongsawasdi, P. and Svasti, J. (1976) The heterogeneity of the protamines from human spermatozoa. Biochim. Biophys. Acta. 434, 462-473.

4. Svasti, J., Pravatmuang, P., Vajanamarhutue, C., Kajadphai, A., Wangthammang, S. and Talupphet, N. (1976) The presence of two igG subclasses in water-buffalo immunoglobulins. J. Sci. Soc. Thailand 2, 56-66.

5. Svasti, J. (1977) An addition at the C-terminus of water-buffalo immunoglobulin lamda chains. Biochem. J. 161, 185-187.

6. Svasti, J. and Panijpan, B. (1977) SDS-polyacrylamide gel electrophoresis: a simple explanation of why it works. J. Chem. Educ. 54, 560-562.

7. Svasti, J. (1979) What is the function of LDH isozymes? TIBS - June N 133-134.

8. Svasti, J. and Talupphet, N. (1979) Improvement in the rsolution of human sperm protamines by use of iodoacetamide as alkylating agent. Biochim. Biophys. Acta. 577, 221-225.

9. Svasti, J., Kurosky, A., Bennett, A., Surarit, R. and Bowman, B.H. (1979) Structure and properties of human plasma vitamin D transport protein (group-specific component) in Vitamin D: Basic Research and its Clinical Application, ed. A.W. Norman et al., Walter de Gruyter, Berlin. pp 149-154.

10. Surarit, R. and Svasti, J. (1980) Effect of ligand binding on the conformation of human plasma vitamin D binding protein (group-specific component). Biochem. J. 191, 401-410.

11. Svasti, J. (1980) A simple laboratory experiment in Biochemistry: the activation and inactivation of sulphydryl and aspartate proteases. Biochem. Ed. 8, 11-15.

12. Svasti, J. (1980) Automated amino acid analysis comes to age: but textbook errors persist. TIBS - January VIII-IX.

13. Toowicharanont, P. and Svasti, J. (1980) A logical approach to the isolation of lactate dehydrogenase isozyme X from human testes: A general rationale for the isolation of homotetrameric LDH isozymes. Experientia 36, 37-38.

14. Anguravirutt, S. and Svasti, J. (1981) A new procedure for the purification of rat testis-specific histone TH2B involving affinity-related chromatography. Arch. Biochem. Biophys. 210, 412-416.

15. Surinrut, P., Svasti, J. and Surarit, R. (1981) Improved purification and fluorescence changes upon activation of human seminal plasma acidic protease proenzyme. Biochem. Biophys. Acta. 659, 38-47.

16. Svasti, J. (1981) Tenth anniversary of the Federation of Asian and Oceanian Biochemists (FAOB). J. Sci. Soc. Thailand 7, 133-135.

17. Surarit, R. and Svasti, J. (1982) Human plasma vitamin D binding protein: conformation and structure. In: Vitamin D, Chemical, Biochemical and Clinical Endocrinology of Calcium Metabolism (A.W. Norman et al., Eds.) Walter de Gruyter and Co., Berlin & New York. pp 1187-1190.

18. Svasti, J. (1983) Biochemistry explained by pictures (book review). Trends in Biochem. Sci. 8, 115-116.

19. Wattanaseree, J. and Svasti, J. (1983) Human testis-specific histone TH2B: fractionation and peptide mapping. Arch. Biochem. Biophys. 225, 892-897.

20. Reid, W.A., Vongsorasak, S.L., Svasti, J., Valler, M.J. and Kay, J. (1984) Identification of the acid proteinase in human seminal fluid as a gastricsin originating in the prostate. Cell Tiss. Res. 236, 597-600

21. Boontrakulpoontawee, P., Yongsuwan, S., Svasti, J., Winichagoon, P. and Fucharoen, S. (1986) Characterization of hemoglobin variants in Thailand. In: Contemporary Themes in Biochemistry, (ICSU Short Reports Vol. 6), ed. Kon, O.L., et al. Cambridge University Press, 606-607

22. Manavanich, C., Anguravirutt, S. and Svasti, J. (1986) Effect of gossypol on lactate dehydrogenase isozymes of the rat. In: Contemporary Themes in Biochemistry (ICSU Short Reports, vol. 6), ed. O.L. Kon et al, Cambridge University Press, Singapore. 304-305.

23. Svasti, M.R.J. (1986) Analysis of amino acid sequence. In: Application of Genetic Engineering on Tropical Disease Pathogens with Special Reference to Plasmodia: a laboratory manual of selected techniques (Panyim, S., Wilairat, P. and Yuthavong, Y. eds.), UNDP/ World bank/WHO TDR, 247-259.

24. Svasti, M.R.J. (1986) Scientific cooperation through Societies, Federations and Unions: some experiences from the biochemical community in Thailand. J. Sci. Soc. Thailand 12, 119-125.

25. Vongsorasak, L. and Svasti, J. (1986) Gossypol prevents activation of purified proenzyme of human seminal plasma acidic proteinase. Biochim. Biophys. Acta. 883, 271-276.

26. Boontrakoonpoontawee, P., Svasti, J., Fucharoen, S. and Winichagoon, P. (1987) Identification of Hb leporr-Washington-Boston in association with HbE [26(B8)GLU to LYS] in a Thai female. Hemoglobin 11, 309-316.

27. Svasti, J., Srisomsap, C., Siriboon, W., Fucharoen, S., Winichagoon, P. and Pravatmuang, P. and Surarit, R. (1993) The structure of abnormal hemoglobins in Thailand. Recent Advances in Molecular and Biochemical Research on Proteins (Wei, Y.-H., Chen, C.-S. and Su, J.-C., eds), World Scientific Press, Singapore pp. 197-200.

28. Svasti, M.R.J. (1987) A theory of circum-motion. J. Sci. Soc. Thailand 13, 185-188.

29. Svasti, M.R.J. (1987) Academic positions and careers in science at Thai universities. J. Sci. Soc. Thailand 13, 63-69.

30. Yongsuwan, S., Svasti, J. and Fucharoen, S. (1987) Decreased heat stability found in Hemoglobin Queens. Hemoglobin 11, 567-570.

31. Boontrakulpoontawee, P., Svasti, J., Fucharoen, S. and Winichagoon, P. (1988) Double heterozygosity for HbE and a lepore-type hemoglobin in a Thai woman. Thalassemia: Pathophysiology and Management Part A (Fucharoen, S., Rowley, P.T. and Paul, N.W., eds.), Liss, Alan R. Inc., New York, 269-274.

32. Svasti, M.R.J. (1988) The properties and mechanism of action of enzymes. Science Magazine 41, 333-340.

33. Svasti, M.R.J. (1989) Activation and inactivation of sulphysryl and aspartate proteases. In: Practical Biochemistry for Colleges (Wood, E.J., ed.) Pergammon Press, Oxford, 9-11.

34. Svasti, M.R.J. (1989) Improved quality of llife for the mentally retarded. J. Pediat. Soc. Thailand 28, 1-5.

35. Svasti, J. and Surarit, R. (1991) Biochemical education in Thailand: past, present and future. Biochem. Educ. 19, 129-135.

36. Svasti, J. (1992) Federation of Asian and Oceanian Biochemists: where now after twenty years. Trends in Biochem. Sci. 17, 53-55.

37. Svasti, J. and Surarit, R. (1992) A survery of introductory biochemistry courses at Thai universities. Biochem. Educ. 20, 204-209.

38. Siriboon, W., Srisomsap, C., Winichagoon, P., Fucharoen, S. and Svasti, J. (1993) Identification of Hb C [beta6 (A3) Glu to Lys] in a Thai male. Hemoglobin 17, 419-425.

39. Svasti, J., Surarit, R., Srisomsap, C., Pravatmuang, P., Wasi, P., Fucharoen, S., Blouquit, Y., Galacteros, F. and Rosa, J. (1993) Identification of Hb Anantharaj [alpha11 (A9) Lys to Glu] as Hb J-Wenchang- Wuming [alpha11 (A9) Lys to Gln]. Hemoglobin 17, 453-455.

40. Surarit, R. and Svasti, J. (1994) Enzymes in dialy life. Sukhothai Thammatiraj Open University. 38-44.

41. Surarit, R., Benjavongkulchai, E. and Svasti, J. (1994) A laboratory experiment on dental caries. Biochem. Educ. 22, 45-47.

42. Svasti, J., Boontrakulpoontawee, P., Yongsuwan, S., Sarikaputi, M., Siriboon, W., Srisomsap, C., Fucharoen, S., Winichagoon, P., Pravatmuang, P. and Surarit, R. (1994) Structural analysis of proteins in Thailand: identification of abnormal hemoglobin. Pure & Appl. Chem. 66, 105-110.

43. Svasti, J., Srisomsap, C., Siriboon, W., Fuchroen, S., Winichagoon, P., Pravatmuang, P. and Surarit, R. (1994) The structure of abnormal hemoglobins in Thailand. In: Recent Advances in Molecular and Biochemical Research on Proteins (Wei, Y.H., Chen, C.S. and Su, J.C., Eds) World Scientific Press, Singapore. 197-200.

44. Sermsuvityawong, K., Svasti, M.R.J., Sawangareetrakul, P., Kisamanonta, P. and Chulavatnatol, M. (1995) Aggregation of cassava linamarase. J. Sci. Soc. Thailand 24, 283-292.

45. Suginta, W. and Svasti, J. (1995) Purification and properties of beta-galactosidase from Hibiscus sabdariffa L. var. altissima. J. Sci. Soc. Thailand 21, 183-186.

46. Surarit, R., Svasti, M.R.J. Srisomsap, C., Suginta, W., Khunyoshyeng, S., Nilwarangkoon, S., Harnsakul, P. and Benjavongkulchai, E. (1995) Screening of glycohydrolase enzymes in Thai plant seeds for potential use in oligosaccharide synthesis. J. Sci. Soc. Thailand 21, 293-303.

47. Benjavongkulchai, E., Surarit, R., Bucke, C. and Svasti, M.R.J. (1996) Synthesis of oligosaccharides by dextransucrase from a local strain of Streptococcus mutants. J. Sci. Soc. Thailand. 22, 105-110.

48. Srisomsap, C., Svasti, J., Surarit, R., Champattanachai, V., Boonpuan, K., Sawangareetrakul, P., Subhasitanont, P. and Chokchaichamnankit, D. (1996) Isolaion and characterization of beta-D-glucosidase/beta-D-fucosidase from Dalbergia cochinchinensis pierre. J. Biochem. 119, 585-590.

49. Surarit, R., Matsui, H., Chiba, S., Svasti, J. and Srisomsap, C. (1996) Chemical modification of beta-glucosidase/beta-fucosidase from Dalbergia cochinchinensis pierre by conduritol B epoxide. Biosci. Biotech. Biochem. 60, 1265-1268.

50. Svasti, J., Srisomsap, C., Surarit, R., Benjavongkulchai, E., Suginta, W., Khunyoshyeng, S., Champattanachai, V., Nilwarangkoon, S. and Rungvirayudx, S. (1996) Potential applications of plant glycohydrolases for oligosaccharide synthesis. In: Protein Structure-Function Relationship. (Zaidi, Z.H. and Smith, D.L., Eds.)Plenum Press, New York, 249-257.

51. Surarit, R., Matsui, H., Chiba, S., Svasti, J. and Srisomsap, C. (1997) Evidence for a Single Active Site in beta-D-Glucosidase/beta-D-Fucosidase from Dalbergia cochinchinensis Seeds. Biosci. Biotech. Biochem. 61, 93-95.

52. Svasti, S., Chungjatupornchai, W. and Panyim, S. (1998) Influence of the mRNA secondary structures on the expression of a giant catfish Pangasianodon gigas growth hormone gene in E.coli. Asia Pac. J. Mol. Biol. Biotechnol. 6, 21-27.

53. Wongwithoonyaporn, P., Bucke, C. and Svasti, J. (1998) Separation and specificity study of alpha-mannosidases from Vignan umbellata. Biosci. Biotech. Biochem. 62, 613-621.

54. Itchayanan, D., Svasti, J., Srisomsap, C., Winichagoon, P. and Fucharoen, S. (1999) Hb G-Coushatta [beta-22(B4)Glu to Ala] in Thailand. Hemoglobin 23, 69-72.

55. Itchayanan, D., Svasti, J., Srisomsap, C., Winichagoon, P. and Fucharoen, S. (1999) Identification of Hb J-Buda [alpha-61 (E10)Lys to Asn] in a Thai female. Hemoglobin 23, 183-186.

56. Srisomsap, C., Wasant, P., Svasti, M.R.J., Chokchaichamnankit, D. and Liammongkolkul, S. (1999) Plasma amino acid and urine organic acid analyses of methylmalonic acidemia in a Thai infant Southeast Asian J. Trop. Med. Public Health. 30(2), 140-142.

57. Srisomsap, C., Subhasitanont, P., Techasakul, S., Surarit, R. and Svasti, J. (1999) Synthesis of homo- and hetero-oligosaccharides by Thai rosewood beta-glucosidase. Biotechnol. Lett. 21, 947-951.

58. Svasti, J., Chantragan, S., Techasakul, S. and Surarit, R. (1999) Dalcochinin-8'-O-beta-D-glucoside and its beta-glucosidase enzyme from Dalbergia cochinchinensis. Phytochemistry 50, 739-743.

59. Svasti, J., Srisomsap, C., Itchayanan, D., Limwuttiwong, A., Siriboon, W., Winichagoon, P. and Fucharoen, S. (1999) Recent studies on the abnormal hemoglogins found in Thailand. J. Chem. Soc. Pak. 21, 281-288.

60. Svasti, M.R.J., Srisomsap, C., Winichagoon, P. and Fucharoen, S. (1999) Detection and structural analysis of abnormal hemoglobins found in Thailand. Southeast Asian J. Trop. Med. Publ. Hlth. 30(2), 88-93.

61. Wasant, P., Svasti, M.R.J., Srisomsap, C., Liammongkolkul, S., Naylor, E.D. and Matsumoto, I. (1999) Inherited metabolic disorders in Thailand - Siraraj experience. Southeast Asian J. Trop. Med. Public Health. 30(2), 124-137.

62. Cairns, J.R.R., Champattanachai, V., Srisomsap, C., Wittman-Leibold, B., Thiede, B. and Svasti, J. (2000) Sequence and expression of Thai rosewood beta-glucosidase/beta-fucosidase, a family1 flycosyl hydrolase glycoprotein. J. Biochem. 128, 999-1008.

63. Lirdprapamongkol, K. and Svasti, J. (2000) Alkyl glucoside synthesis using Thai rosewood beta-glucosidase. Biotechnol. Lett. 22,1889-1894.

64. Yodsowan, B., Svasti, J., Srisomsap, C., Winichagoon, P. and Fucharoen, S. (2000) Hb Siam [alpha15(A13)Gly to Arg] is a GGT to CGT mutation in the alpha1-globin gene. Hemoglobin 24(1), 71-75.

65. Imai, K., Tientadakul, P., Opartkiattikul, N., Luenee, P., Winichagoon, P., Svasti, J. and Fucharoen, S. (2001) Detection of haemoglobin variants and inference of their functional properties using complete oxygen dissociation curve measurement. Br. J. Haematol. 112, 483-487.

66. Svasti, J. (2001) Bioscience and its impact on developing countries. EMBO Rep. 2(8), 648-650.

67. Svasti, S., Wasant, P., Tiensuwan, M., Sawangareetrakul, P., Srisomsap, C., Pangkanon, S., Boonpuan, K. and Liammongkolkul, S. (2001) Normal plasma free amino acid levels in Thai children. J. Med. Assoc. Thailand 84, 1558-1568.

68. Svasti, S., Yodsowon, B., Sriphanich, R., Winichagoon, P., Boonkhan, P., Wuwanban, T., Sawangareetrakul, P., Srisomsap, C., James, R.K., Svasti, J. and Fucharoen, S. (2001) Association of Hb Hope [beta136(H14)Gly to Asp] and Hb H Disease. Hemoglobin 25(4), 429-435.

69. Sawangareetrakul, P., Svasti, S., Yodsowon, B., Winichagoon, P., Srisomsap, C., Svasti, J. and Fucharoen, S. (2002) Double heterozygosity for Hb Pyrgos [beta 83(EF7) Gly to Asp] and Hb E [beta26(B8) Glu to Lys] found in association with alpha-thalassemia. Hemoglobin 26, 191-196.

70. Srisomsap, C., Subhasitanont, P., Otto, A., Mueller, E.C., Punyarit, P., Wittman-Liebold, B. and Svasti, J. (2002) Detection of cathepsin B up-regulation in neoplastic thyroid tissues by proteomic analysis. Proteomics 2, 706-712.

71. Turbpaiboon, C., Svasti, S., Sawangareetakul, P., Winichagoon, P., Srisomsap, C., Siritanaratkul, N., Fucharoen, S., Wilairat, P. and Svasti, J. (2002) Hb Siam [alpha15(A13)Gly to Arg(alpha1) (GGT to CGT)] is a typical alpha chain hemoglobinopathy without an alpha-thalassemic effect. Hemoglobin 26, 77-81.

72. Wasant, P., Srisomsap, C., Liammongkolkul, S. and Svasti, M.R.J. (2002) Urea cycle disorders in Thai infants: a report of 5 cases. J. Med. Assoc. Thailand 85(2), S720-731.

73. Wasant, P., Svasti, M.R.J., Srisomsap, C. and Liammongkolkul, S. (2002) Inherited metabolic disorders in Thailand. J. Med. Assoc. Thailand 85(2), S700-709.

74. Champattanachai, V., Ketudat Cairns, J.R., Shotelersuk, V., Keeratichamroen, S., Sawangareetrakul, P., Srisomsap, C., Kaewpaluek, V. and Svasti, J. (2003) Novel mutations in a Thai patient with methylmalonic acidemia. Mol. Genet. Metab. 79, 300-302.

75. Lirdprapamongkol, K., Mahidol, C., Thongnest, S., Prawat, H., Ruchirawat, S., Srisomsap, C., Surarit, R., Punyarit, P. and Svasti, J. (2003) Anti-metastatic effects of aqueous extract of Helixanthera parasitica. J. Ethnopharmacol. 86, 253-256.

76. Ngiwsara, L., Srisomsap, C., Winichagoon, P., Fucharoen, S. and Svasti, J. (2003) Hb Kodaira II [beta146(HC3) His to Gln] detected in Thailand. Hemoglobin 27, 37-39.

77. Opassiri, R., Cairns, J.R.K., Akiyama, T., Wara-Aswapati, O., Svasti, M.R.J. and Esen, A. (2003) Characterization of a rice beta-glucosidase highly expressed in flower and germinating shoot. Plant Sci. 165, 627-638.

78. Svasti, J., Phongsak, T. and Sarnthima, R. (2003) Transglucosylation of tertiary alcohols using cassava beta-glucosidase. Biochem. Biophys. Res. Commun. 305, 470-475.

79. Chaiyen, P., Sucharitakul, J., Svasti, M.R.J., Entsch, B., Massey, V. and Ballou, D.P. (2004) Use of 8-substituted-FAD analogues to investigate the hydroxylation mechanism of the flavoprotein 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase. Biochemistry 43, 3933-3943.

80. Kubota, M., tsuji, M., Nishimoto, M., Wongchawalit, J., Okuyama, M., Mori, H., Matsui, H., Surarit, R., Svasti, J., Kimura, A. and Chiba, S. (2004) Localization of alpha-glucosidases I, II and III in organs of European honeybees, Apis mellifera L. and the origin of alpha-glucosidase in honey. Biosci. Biotech. Biochem. 68, 2346-2352.

81. Ngiwsara, L., Srisomsap, C., Winichagoon, P., Fucharoen, S. and Svasti, J. (2004) Two cases of compound heterozygosity for Hb Hekinan [alpha27(B8)Glu to Asp (alpha1)] and alpha-thalassemia in Thailand. Hemoglobin 28, 145-150.

82. Opassiri, R., Hua, Y.L., Wara-Aswapati, O., Akiyama, T., Svasti, J. Esen, A. and Ketudat Cairns, J.R. (2004) beta-Glucosidase, exo-beta-glucosidase, exo-beta-glucanase and pyridoxine transglucosylase activities of rice BGlu1. Biochem. J. 379, 125-131.

83. Srisomsap, C., Sawangareetrakul, P., Subhasitanont, P., Panichakul, T., Keeratichamroen, S., Lirdprapamongkol, K., Chokchaichamnankit, D., Sirisinha, S. and Svasti, M.R.J. (2004) Proteomic analysis of cholangiocarcinoma cell line. Proteomics 4, 1135-1144.

84. Suginta, W., Vongsuwan, A., Songsiriritthigul, C., Prinz, H., Estibeiro, P., Duncan R.R., Svasti, J. and Fothergill-Gilmore, L.A. (2004) An endochitinase A from Vibrio carchariae: cloning, expression, mass and sequence analyses and chitin hydrolysis. Arch. Biochem. Biophys. 424, 171-180.

85. Buranaprapuk, A., Chaivisuthangkura, P., Svasti, J. and Kumar, C.V. (2005) Efficient photocleavage of lysozyme by a new chiral probe. Lett. Org. Chem. 2, 554-558.

86. Cairns, J.R.K., Keeratichamroen, S., Sukcharoen, S., Champattanachai, V., Ngiwsara, L., Lirdprapamongkol, K., Liammongkolkul, S., Srisomsap, C., Surarit, R., Wasant, P. and Svasti, J. (2005) The Molecular Basis Of Mucopolysa Polysaccharidosis Type I In Two Thai Patients. Southeast Asian J. Trop. Med. Pub. Health

87. Chuankhayan, P., Hua, Y., Svasti, J., Sakdarat, S., Sullivan, P.A. and Ketudat, Cairns, J.R. (2005) Purification of an isoflavonoid 7-O-beta-apiosyl-glucoside beta-glycosidase and its substrates from Dalbergia nigrescens Kurz. Phytochemistry 66, 1880-1889.

88. Hommalai, G., Chaiyen, P. and Svasti, J. (2005) Studies on the transglucosylation reactions of cassava and Thai rosewood beta-glucosidases using 2-deoxy-2-fluoro-glycosyl-enzyme intermediates. Arch. Biochem. Biophys. 442, 11-20.

89. Lirdprapamongkol, K., Sakurai, H., Kawasaki, N., Min-Kyung, Chooa., Saitoh, Y., Aozukaa, Y., Singhirunnusorn, P., Ruchirawat, S., Jisnuson, Svasti, M.R.J. and Saiki, I. (2005) Vanillin suppresses in vitro invasion and in vivo metastasis of mouse breast cancer cells European Journal of Pharmaceutical Sciences 25, 57-65.

90. Mahakhan, P., Chobvijuk, C., Ngmjarearnwong, M., Trakulnalermsai, S., Bucke, C., Svasti, J., Kanlayakrit, W., and Chitradon, L. (2005) Molecular hydrogen production by a thermotolerant Rubrivivax gelatinosus using raw cassava starch as an electron donor. ScienceAsia 31, 415-424.

91. Ngiwsara, L., Srisomsap, C., Winichagoon, P., Fucharoen, S., Sae-Ngow, B. and Svasti, J. (2005) Hb Kurosaki [alpha7(A5)Lys to Glu (AAG to GAG)]: an alpha2-globin gene mutation found in Thailand. Hemoglobin. 29, 155-159.

92. Suginta, W., Vongsuwan, A., Songsiriritthigul, C., Svasti, J. and Prinz, H. (2005) Enzymatic properties of wild-type and active site mutants of chitinase A from Vibrio carchariae, as revealed by HPLC-MS. FEBS J. 272, 3376-3386.

93. Svasti, J. (2005) My experiences as an IUB travel fellow. IUBMB Life 57, 255

94. Svasti, J., Srisomsap, C., Subhasitanont, P., Keeratichamroen, S., Chokchaichamnankit, D., Ngiwsara, L., Chimnoi, N., Pisutjaroenpong, S., Techasakul, S. and Chen, S.T. (2005) Proteomic profiling of cholangiocarcinoma cell line treated with pomiferin from Derris malaccensis. Proteomics. 5, 4504-4509.

95. Svasti, M.R.J. (2005) Thirty Years of ScienceAsia, Journal of the Science Society of Thailand ScienceAsia 31, 1-3.

96. Wasant, P., Vatanavichien, N., Srisomsap, C., Sawangareetrakul, P., Liammongkolkul, S. and Svasti, J. (2005) Retrospective Study of Patients with Suspected Inborn Errors of Metabolism at Siriraj Hospital, Bangkok, Thailand (1997-2001) J. Med. Assoc. Thai 88, 746-753.

97. Wasant, P., Viprakasit, V., Srisomsap, C., Liammongkolkul, S., Ratanarak, P., Sathienkijakanchai, A. and Svasti, J. (2005) Arginosuccinate synthetase deficiency: mutation analysis in 3 Thai patients. Southeast Asian J. Trop. Med. Public Health 36, 757-761.

98. Arthan, D., Kittakoop, P., Esen, A., and Svasti, J. (2006) Furostanol glycoside 26-O-beta-glucosidase from the leaves of Solanum torvum. Phytochemistry 67, 27-33.

99. Yongvanich, T. and Svasti, J. (1984) Structural differences between somatic H2B and testis-specific TH2B histones of the rat. Experientia 40, 845-846.

100. Reid, W.A., Liddle, C.N., Svasti, J. and Kay, J. (1985) Gastricsin in the benign and malignant prostate. J. Clin. Pathol. 38, 639-643.

101. Vongsorasak, L. and Svasti, J. (1985) Inhibition of liquefaction and proteolysis of human semen by gossypol. Int. J. Androl. 8, 472-483.

102. Thammasirirak, S., Ponkham, P., Preecharram, S., Khanchanuan, R., Phonyothee, P., Daduang, S., Srisomsap, C., Araki, T. and Svasti, J. (2006) Purification, characterization and comparison of reptile lysozymes. Comp. Biochem. Physiol. C. Toxicol. Pharmacol. 143: 209-17.

B. Editorials, Reviews and Other Academic Articles

1. Svasti, M.R.J. (1981) Tenth Anniversary of the Federation of Asian and Oceanian
Biochemists (FAOB) J. Sci. Soc. Thailand 7, 133-135.

2. Svasti, M.R.J. (1985) Principles of Biochemical Separation. In Proceedings, Workshop on "The Separation of Biochemical Compounds", pp. 1-17, Srinakarintrvirot University, Bangkok. In Thai.

3. Svasti, M.R.J. (1985) Strategies in the Separation of Biochemical Compounds. In
Proceedings, Workshop on "The Separation of Biochemical Compounds", pp.113-126,
Srinakarintrvirot University, Bangkok. In Thai.

4. Svasti, M.R.J. and Boontrakulpoontawee, P. (1985) Abnormal Hemoglobins. Science
Magazine, 39, 491-501. In Thai.

5. Svasti, M.R.J. (1986) Enzymes Used in the Cutting and Joining of DNA. Proceedings, Workshop on "Basic Techniques in Genetic Engineering", pp. 65-80, Khon Khaen University. In Thai.

6. Svasti, M.R.J. (1985) A Call for Papers. J. Sci. Soc. Thailand 11, 1-3.

7. Svasti, M.R.J. (1985) Integrity and Judgement in Science. J. Sci. Soc. Thailand 11, 141- 145.

8. Svasti, M.R.J. (1986) Scientific Cooperation through Societies, Federations and Unions: some experiences from the biochemical community in Thailand. J. Sci. Soc. Thailand 12, 119-125.

9. Svasti, M.R.J. (1987) The Properties of Enzymes. In Proceedings, Workshop on "Enzymes and Their Applications", pp. 1-28, Mahidol University, Bangkok. In Thai.

10. Svasti, M.R.J. (1987) Academic Positions and Careers in Science at Thai Universities. J. Sci. Soc. Thailand 13, 63-69.

11. Svasti, M.R.J. (1987) A Theory of Circum-motion. J. Sci. Soc. Thailand 13, 185-188.

12. Svasti, M.R.J. (1988) The Properties and Mechanism of Action of Enzymes. Science
Magazine 41, 333-340. In Thai.

13. Svasti, M.R.J. (1989) Improved Quality of Life for the Mentally Retarded. J. Pediat. Soc. Thailand 28, 993-998.

14. Svasti, M.R.J. (1990) The Teaching of Biochemistry in Thailand. In Proceedings, Workshop on "More Efficient Teaching of Biochemistry", pp. 1-16, Sukhothai Thammatiraj University, Bangkok

15. Svasti, J. and Surarit, R. (1992) Survey of the Content of Biochemistry Courses Presently Being Taught at Tertiary Level. In Proceedings, Workshop on "Strategies for Developing Curriculum and Teaching in Biochemistry", pp. 36-58, Srinakarintrwirot University Prasarnmitr, Bangkok. In Thai.

16. Surarit, R. and Svasti, J. (1994) Enzymes in Daily Life. Sukhothai Thammatiraj Open University Journal. 7, 38-44. In Thai.

17. Svasti, M.R.J. (1996) To Be or Not To Be: That is the Question. Mahidol Univ. J. 3, 151- 152.

18. Svasti, M.R.J. (1998) International Relations at Mahidol University. Mahidol Univ. J. 5, 77-83.

19. Svasti, M.R.J. (2001) ScienceAsia and Its Role in Enhancing a Research Culture in Thailand. ScienceAsia 27, 73-74.

20. Svasti, M.R.J. (2005) Thirty Years of ScienceAsia, Journal of the Science Society of Thailand. ScienceAsia 31, 1-3.

21. Svasti, J. (2005) My Experience as an IUB Travel Fellow. IUBMB Life In Press.

C. Textbooks and Guidebook
1. Svasti, M.R.J. (1978) in Laboratory Experiments and Basic Concepts in Biochemistry (Rungruangsak, K. and Svasti, M.R. J., eds.), Amarin Press, Bangkok. In Thai.
1. Chapter 1: Composition and Functions of Cells (pp. 1-17)
2. Chapter 6: Amino Acids and Proteins (pp. 172-223)
3. Chapter 7: Enzymes (pp. 224-269)

2. Svasti, M.R.J. (1987) in Biochemistry, 2530, Third Revised Edition (Chulavatnatol, M., ed.), Sor Sor Ltd., Bangkok.. In Thai.
1. Chapter 6: Amino Acids and Proteins (pp. 107-145)
2. Chapter 7: Enzymes and Biochemical Reactions (pp. 147-174)
3. Chapter 8: Assembly of Biomolecules (pp. 175-188)

3. Svasti, M.R.J. (1999) in Biochemistry, 2542, Fourth Revised Edition (Chulavatnatol, M., and Komaratat, P., eds.), ISBN 974-86639-8-1, Jirrus Printing Ltd, Bangkok.
1. Chapter 6: Amino Acids and Proteins (pp. 89-123)
2. Chapter 7: Enzymes and Biochemical Reactions (pp. 125-150)
3. Chapter 8: Assembly of Biomolecules (pp. 151-161)

4. Svasti, M.R.J., Suwanchinda, B. and Phruthonkul, S. (eds.) (1999) Guidebook for Speech Writing. ISBN 974-663-059-8.
 
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