New Pancreatic Cancer Animal Models to aid Novel Therapy Development. Austrianova Singapore announced today that they and their partners have created a mouse model that mimics human pancreatic cancer.
This research has just been published in the peer-reviewed online, open access journal, PLoS One. The paper describes mouse models derived from human pancreatic tumours in which tumour cells were implanted in the pancreas, unlike the usual subcutaneous models. These new models are designed for advancing and fine tuning the Cell-in-a-Box® pancreatic cancer encapsulated live-cell treatments that has already been successfully used in humans and is being prepared for late stage pancreatic cancer clinical trials by Austrianova Singapore together with Nuvilex, Inc.
The Chairman for Austrianova Singapore, Dr. Walter Gunzburg, commented “The pancreatic cancer mouse models were created with our partners at the University of Veterinary Medicine, in Vienna, Austria and are important clinically since they mimic human pancreatic cancer. Most cancers, including pancreatic, involve changes in only one organ, location and cell type. The most important aspect of this model system is the location of the tumour solely to the pancreas, which differs from most other model systems”.
Austrianova Singapore’s Chief Executive, Dr. Brian Salmons, stated, “We are excited by these new models since they should provide greater insight into how the therapy works and also allow potential improvements as we continue to advance the ongoing human pancreatic cancer clinical trials being planned with Nuvilex. From what we have learned to date, these models are more relevant for the human disease and should thus aid in the development and robust in vivo testing of new treatments."
About Austrianova Singapore
Austrianova Singapore (SG Austria) Pte Ltd, is a Singapore based biotech company that develops and applies its proprietary cell encapsulation technology (Cell-in-a-Box® and Bacin-a-Box®) to the development of novel treatments for cancer and other diseases as well as being a solution provider for various aspects of cell growth and protection via live cell encapsulation for biotech and pharmaceutical companies.